|
TERRY HAMBLIN |
Marc asked about side
effects of Novantrone.
Novantrone (or Mitoxantrone) is very similar to adriamycin (it's blue
instead of red). It is an anthracenedione rather than an anthracycline,
but it is
chemically very similar. It has all the anthracycline side effects. When
it ws
introduced it was said to be less toxic especially in the elderly, but
it is
hard to establish this. It cause bone marrow suppression (lasting a
little
longer than adriamycin), but a bit less hair loss. It was supposed to
cauise
less cardiac damage but the data are not very convincing.
I'm not very convinced, having used both for many years that there is
much
to chose between adriamycin and Novantrone. |
