Palliative care:
Treatment that relieves symptoms, such as pain, but is not expected to cure the disease. The main purpose is to improve the patient's quality of life.
Pancytopenia:
A condition in which there are reduced numbers of all types of blood cells.
Partial remission:
The reduction, but not complete disappearance, of cancer in response to therapy.
Pathologist:
A doctor who specializes in examining tissue and diagnosing disease.
-penia:
A suffix which indicates abnormally low numbers of blood cells. Examples include, leukopenia, thrombocytopenia, and erythropenia.
Peptide:
Two or more amino acids chemically bonded to form a single molecule.
Peripheral blood:
Blood circulating throughout the body.
Peripheral neuropathy:
Numbness, tingling, burning, and weakness in the extremities This condition usually affects the hands and feet and may occur as a complication of chemotherapy.
Performance Status:
A classification used for describing the status of cancer patients. The World Health Organization (WHO) defines performance status in terms of the following grade levels: 0 – able to carry out all normal activity without restriction; 1 – restricted in physically strenuous activity but ambulatory and able to do light work; 2 – ambulatory and capable of self-care but unable to carry out any work; 3 – capable of only limited self-care confined to bed or chair 50% or more of waking hours; and 4 – completely disabled and cannot carry on any self-care.
Petechiae:
Tiny red spots under the skin; often a symptom of leukemia.
Phagocytosis:
The process by which phagocytes (literally, cell eaters) surround and destroy micro-organisms or any foreign matter.
Pheresis:
A procedure in which blood is removed from a donor, separated, and a portion retained, with the remainder being returned to the donor.
Philadelphia chromosome:
An abnormal chromosome that is formed when part of chromosome 9 attaches to chromosome 22 (translocation). This abnormality is found in nearly all cases of chronic myeloid leukemia. Also called as Ph1.
Plasma:
The liquid portion of the blood.
Plasma cells:
Large cells derived from the lymphocytes that form antibodies. Plasma cells are normally restricted to the bone marrow and lymph nodes and are not found in circulating blood.
Platelets:
Blood cells that help to control bleeding by inducing clotting. Also called thrombocytes.
Pneumocystosis:
Pneumonia resulting from infection with Pneumocystis carinii, frequently seen in immunologically compromised or steroid-treated individuals.
Polymerase chain reaction (PCR):
A laboratory process in which a particular DNA segment from a mixture of DNA chains is rapidly replicated, producing a large, readily analyzed sample of a piece of DNA.
Postherpetic neuralgia (PHN):
Pain that continues after the rash from shingles has healed.
Preleukemic condition:
A disease of the blood that is not yet cancer but may become leukemia in the future
Progenitor cell (also Precursor cell):
An immature cell in the bone marrow which is responsible for producing mature blood cells.
Prognosis:
The probable outcome or course of a disease; the chance of recovery.
Prolymphocytic leukemia (PLL):
A variant of chronic lymphocytic leukemia in which the malignant cells have a more immature appearance.
Prophylaxis:
An attempt to prevent disease.
Protein:
A large number of amino acids chemically bonded in a chain. Proteins are large peptides.
Protocol:
A schedule of treatment.
Purging:
Removal of tumour cells from harvested bone marrow or blood before autologous transplantation.
Purpura:
A condition characterized by the occurrence of purple spots on the skin, often accompanied by bleeding from the gums.